The recent finding that dengue fever has emerged in Houston, Texas—the first major United States city in modern times with autochthonous dengue—adds to previous evidence indicating that the Gulf Coast of the Southern US is under increasing threat from diseases thought previously to affect only developing countries.
Extreme poverty and a warm, tropical climate are the two most potent forces promoting the endemicity of neglected tropical diseases in Africa, Asia, and Latin America. Now, these same forces are also widely prevalent in the five states of the US Gulf Coast—Texas, Louisiana, Mississippi, Alabama, and Florida.